Dosage Information for Koselugo: Forms, Strengths, Administration, and Additional Details

Koselugo Administration: Forms, Dosages, Methods, and Further Details

Koselugo, a kinase inhibitor, is a new oral treatment for plexiform neurofibromas (PN) in children aged 2 years and older with neurofibromatosis type 1 (NF1). This medication comes in the form of capsules, available in two strengths: 10 milligrams (mg) and 25 mg.

To ensure effective and safe use, it's crucial to follow your child's prescribed dosage. Typically, the dosage should be taken approximately 12 hours apart. The dosage is based on body surface area (BSA) calculations, and the specific doses for treating PN in children with NF1 vary based on BSA, as detailed in the table provided.

It's important to note that Koselugo should be taken whole with water, either with or without food. Do not let your child chew the capsules or let them dissolve in their mouth. If your child has difficulty swallowing the capsules, consult with their doctor or pharmacist.

In case of an overdose, immediate action is required. Call their doctor right away or contact America's Poison Centers at 800-222-1222 or online. If your child has severe symptoms after taking too much Koselugo, call 911 or take them to the nearest emergency room immediately.

The active ingredient in Koselugo is selumetinib. This medication is a long-term treatment, usually taken for as long as it is safe and effective for your child. However, the recommended dose for children under 12 years with PN and NF1 is typically individualized by weight and clinical assessment. Careful monitoring and potential dose modification may be required due to interactions with other drugs.

As with any medication, it's essential to adhere to the prescribed dosage. Do not give your child more Koselugo than their doctor prescribes. If your child vomits after taking a dose of Koselugo, do not give them an extra dose. Wait for the next usual time to give them their dose.

In conclusion, Koselugo offers a new hope for children suffering from plexiform neurofibromas. By understanding how to correctly administer this medication and what to do in case of an overdose, parents can ensure their child's safety and well-being. Always consult with your child's doctor or pharmacist for any questions or concerns regarding Koselugo.