NFL Kickoff Game 2025 Prediction, Odds, Time: Expert's Forecast on a 24-10 Winning Streak for the Matchup between Eagles and Cowboys

The 2025 NFL season is just around the corner, and the highly anticipated Kickoff Game will pit two division rivals against each other: the Philadelphia Eagles and the Dallas Cowboys. The Eagles are favored to win by 7.5 points, according to odds makers, with the over/under for total points scored set at 47.5.

Last season, the Eagles dominated the NFC East, winning the division for the second time in three years. They capped off their successful campaign with a Super Bowl LIX victory over the Kansas City Chiefs, winning 40-22. A.J. Brown, the Eagles' wide receiver, was a key contributor in the Super Bowl, catching three passes for 43 yards and one touchdown.

Brown had an impressive season overall, playing in 13 games and catching 67 passes for a team-high 1,079 yards (16.1 average) and seven touchdowns. His longest reception of the season was a 67-yard touchdown catch.

On the other side of the field, the Cowboys finished the 2024 season with a record of 7-10. Dak Prescott, the Cowboys' quarterback, missed a good chunk of the season due to injury, which undoubtedly affected their performance. However, Dallas made some significant moves in the off-season, including the acquisition of new offensive weapons like wide receiver George Pickens and a fully healthy offensive line.

CeeDee Lamb, the top returning wide receiver for the Cowboys, led the team with 101 receptions for 1,194 yards (11.8 average) and six touchdowns in 15 games last season. He also had 16 explosive plays of 20 yards or more, including a long of 65 yards, and 54 first-down conversions and 537 yards after the catch.

In a 30-24 loss at San Francisco on Oct. 27, Lamb had a season-high 13 catches for 146 yards and two touchdowns. Despite the Cowboys' struggles last season, analysts are optimistic about their chances against the Eagles, citing Dallas' recent improvements and some skepticism about the Eagles' defense changes after linebacker trades as critical factors that could help the Cowboys cover the spread.

The Cowboys made headlines by trading Micah Parsons to the Packers on Aug. 28, 2025. The impact of this trade on the Cowboys' performance remains to be seen.

Jalen Hurts, the Eagles' quarterback, had a solid season in 2024, completing 68.7% of his passes for 2,903 yards and 18 touchdowns in 15 games. He also rushed for 630 yards and 14 touchdowns.

With both teams preparing for their first game of the 2025 season, fans are eager to see how these two powerhouse teams will match up. The 2025 NFL Kickoff Game promises to be an exciting and competitive contest between the Philadelphia Eagles and the Dallas Cowboys.